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 Quantitative analysis for hydration of unpaired nucleotides in DNA and RNA duplexes |
 Evaluation of molecular crowding effects on tertiary structures of nucleic acids |
 Analyses of biomolecules that function in intracellular crowding dynamics |
 Development of DNA-based biosensor for monitoring pH in vitro and in living cells |
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| Research activities | |
| To reveal the behavior of the biomolecules inside the cell is important not only for the understanding of the inside of the cell system, but also for a potential use of biomolecules as new pharmaceuticals. We are estimating quantitatively for the structures and stabilities of biomolecules such as nucleic acids and proteins under cell-like conditions. Our researches, which are directed by Prof. Sugimoto and carried out by lab. students and the FIBER’s staff aim to develope a system to predict the stability and structure of biomolecules inside a cell. The following are some examples of outline about our researches. | |
about FIBER |
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