Nearest Neighbor Calculator for Nucleic Acids

Sequence: ▼

Chain A: -3'

Chain B: -5'

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Sequence		ΔH^o	ΔS^o	ΔG^o		Number
DNA (5'- to 3'-)	DNA (3'- to 5'-)	ΔH^o	ΔS^o	ΔG^o		Number

ΔH^o

ΔS^o

ΔG^o

0.0 kcal mol⁻¹

0.0 cal mol⁻¹ K⁻¹

0.0 kcal mol⁻¹

[1] SantaLucia,J., Allawi,H.T. and Seneviratne,P.A. (1996) Improved Nearest-Neighbor Parameters for Predicting DNA Duplex Stability †. Biochemistry, 35, 3555–3562.
[2] Sugimoto,N., Nakano,S., Katoh,M. and Matsumura,A. (1995) Thermodynamic parameters to predict stability of RNA/DNA hybrid duplexes. Biochemistry, 34, 11211–11216.
[3] Freier,S.M., Kierzek,R., Jaeger,J.A., Sugimoto,N., Caruthers,M.H., Neilson,T. and Turner,D.H. (1986) Improved free-energy parameters for predictions of RNA duplex stability. Proceedings of the National Academy of Sciences of the United States of America, 83, 9373–9377.
[4] Banerjee, D., Tateishi-Karimata, H., Ohyama, T., Ghosh, S., Endoh, T., Takahashi, S., & Sugimoto, N. (2020). Improved nearest-neighbor parameters for the stability of RNA/DNA hybrids under a physiological condition. Nucleic acids research, 48, 12042-12054.